Reactome | SEMA4D interacts with Plexin-B1:ErbB2

Schema > Reaction > Entries

SEMA4D interacts with Plexin-B1:ErbB2 Show undefined attributes

catalystActivity	[CatalystActivity:10249357] protein tyrosine kinase activity of Plexin-B1:ErbB2 [plasma membrane]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10249359
displayName	SEMA4D interacts with Plexin-B1:ErbB2
eventOf	[Pathway:R-CFA-416572] Sema4D induced cell migration and growth-cone collapse - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-CFA-416594] LARG and PDZ-RhoGEF binds to Plexin-B1 - Canis familiaris
inferredFrom	[Reaction:R-HSA-373750] SEMA4D interacts with Plexin-B1:ErbB2 - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [Complex:R-CFA-419629] Plexin-B1:ErbB2 [plasma membrane] [Complex:R-CFA-373690] SEMA4D dimer [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	SEMA4D interacts with Plexin-B1:ErbB2
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [Complex:R-CFA-373695] SEMA4D:ERBB2:p-Y-PLXNB1 [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-373750
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-416572] Sema4D induced cell migration and growth-cone collapse
(precedingEvent)	[Reaction:R-CFA-416594] LARG and PDZ-RhoGEF binds to Plexin-B1
(inferredTo)	[Reaction:R-HSA-373750] SEMA4D interacts with Plexin-B1:ErbB2

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