Reactome | Talin:RIAM complex: ECM ligands:Integrin alphaIIb beta3:Active (p-Y419)- SRC:PTK2 [plasma membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10248950] protein tyrosine kinase activity of Talin:RIAM complex: ECM ligands:Integrin alphaIIb beta3:Active (p-Y419)- SRC:PTK2 [plasma membrane]
compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-CFA-354073] Autophosphorylation of PTK2 at Y397 - Canis familiaris
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10248942
displayName	Talin:RIAM complex: ECM ligands:Integrin alphaIIb beta3:Active (p-Y419)- SRC:PTK2 [plasma membrane]
hasComponent	[EntityWithAccessionedSequence:R-CFA-201621] PTK2 [cytosol] [Complex:R-CFA-377622] Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-354103] Talin:RIAM complex: ECM ligands:Integrin alphaIIb beta3:Active (p-Y419)- SRC:PTK2 [plasma membrane] - Homo sapiens
maxDepth	7
name	Talin:RIAM complex: ECM ligands:Integrin alphaIIb beta3:Active (p-Y419)- SRC:PTK2
producedByEvent	[Reaction:R-CFA-354066] Translocation of PTK2 to Focal complexes - Canis familiaris
schemaClass	Complex
species	[Species:49646] Canis familiaris
stId	R-CFA-354103
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-CFA-354073] Autophosphorylation of PTK2 at Y397
(physicalEntity)	[CatalystActivity:10248950] protein tyrosine kinase activity of Talin:RIAM complex: ECM ligands:Integrin alphaIIb beta3:Active (p-Y419)- SRC:PTK2 [plasma membrane]
(output)	[Reaction:R-CFA-354066] Translocation of PTK2 to Focal complexes
(inferredTo)	[Complex:R-HSA-354103] Talin:RIAM complex: ECM ligands:Integrin alphaIIb beta3:Active (p-Y419)- SRC:PTK2 [plasma membrane]

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