Reactome | phospho-COP1 [nucleoplasm]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-CFA-349420] p-S387-RFWD2:p-S15-TP53 [nucleoplasm] - Canis familiaris
consumedByEvent	[Reaction:R-CFA-264418] Translocation of COP1 from the nucleus to the cytoplasm - Canis familiaris
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10248024
displayName	phospho-COP1 [nucleoplasm]
endCoordinate	731
hasModifiedResidue	[ModifiedResidue:10248022] O-phospho-L-serine at 387 (in Homo sapiens)
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-349450] p-S387-RFWD2 [nucleoplasm] - Homo sapiens
maxDepth	1
name	phospho-COP1 p-S387-RFWD2 A0A8I3N6U5
producedByEvent	[Reaction:R-CFA-264435] Dissociation of the COP1-p53 complex - Canis familiaris [Reaction:R-CFA-349444] Phosphorylation of COP1 at Ser-387 by ATM - Canis familiaris
referenceEntity	[ReferenceGeneProduct:uniprot:A0A8I3N6U5] UniProt:A0A8I3N6U5
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:49646] Canis familiaris
stId	R-CFA-349450
startCoordinate	1

(input)	[Reaction:R-CFA-264418] Translocation of COP1 from the nucleus to the cytoplasm
(output)	[Reaction:R-CFA-264435] Dissociation of the COP1-p53 complex [Reaction:R-CFA-349444] Phosphorylation of COP1 at Ser-387 by ATM
(hasComponent)	[Complex:R-CFA-349420] p-S387-RFWD2:p-S15-TP53 [nucleoplasm]
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-349450] p-S387-RFWD2 [nucleoplasm]

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