Reactome | XIAP monoubiquinates TLE

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XIAP monoubiquinates TLE Show undefined attributes

catalystActivity	[CatalystActivity:10282959] ubiquitin protein ligase activity of TLE:XIAP [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10282961
displayName	XIAP monoubiquinates TLE
eventOf	[Pathway:R-CFA-3769402] Deactivation of the beta-catenin transactivating complex - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-CFA-3322434] XIAP dissociates from ub-TLE - Canis familiaris
inferredFrom	[Reaction:R-HSA-3322429] XIAP monoubiquinates TLE - Homo sapiens
input	[Complex:R-CFA-3322390] TLE:XIAP [nucleoplasm] [DefinedSet:R-CFA-68524] Ub [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	XIAP monoubiquinates TLE
output	[Complex:R-CFA-3322386] ub-TLE:XIAP [nucleoplasm]
precedingEvent	[Reaction:R-CFA-3322431] XIAP binds TLE - Canis familiaris
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-3322429
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-3769402] Deactivation of the beta-catenin transactivating complex
(precedingEvent)	[Reaction:R-CFA-3322434] XIAP dissociates from ub-TLE
(inferredTo)	[Reaction:R-HSA-3322429] XIAP monoubiquinates TLE

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