Reactome | Activation of NIMA Kinases NEK9, NEK6, NEK7

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Activation of NIMA Kinases NEK9, NEK6, NEK7 Show undefined attributes

created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10330999
displayName	Activation of NIMA Kinases NEK9, NEK6, NEK7
eventOf	[Pathway:R-CFA-2980766] Nuclear Envelope Breakdown - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-CFA-2984220] CDK1:CCNB phosphorylates NEK9 - Canis familiaris [Reaction:R-CFA-2984226] PLK1 phosphorylates NEK9 - Canis familiaris [Reaction:R-CFA-2980720] NEK9 binds NEK6/NEK7 in the cytosol - Canis familiaris [Reaction:R-CFA-2984258] NEK9 phosphorylates NEK6/NEK7 - Canis familiaris
inferredFrom	[Pathway:R-HSA-2980767] Activation of NIMA Kinases NEK9, NEK6, NEK7 - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Activation of NIMA Kinases NEK9, NEK6, NEK7
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49646] Canis familiaris
stId	R-CFA-2980767
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-2980766] Nuclear Envelope Breakdown
(inferredTo)	[Pathway:R-HSA-2980767] Activation of NIMA Kinases NEK9, NEK6, NEK7

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