Reactome | DVL2 binds phosphorylated WWTR1 (TAZ)

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DVL2 binds phosphorylated WWTR1 (TAZ) Show undefined attributes

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10275995
displayName	DVL2 binds phosphorylated WWTR1 (TAZ)
eventOf	[Pathway:R-CFA-2028269] Signaling by Hippo - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-2066299] DVL2 binds phosphorylated WWTR1 (TAZ) - Homo sapiens
input	[EntityWithAccessionedSequence:R-CFA-201694] DVL2 [cytosol] [EntityWithAccessionedSequence:R-CFA-2028665] phospho-WWTR1 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	DVL2 binds phosphorylated WWTR1 (TAZ)
output	[Complex:R-CFA-2066300] p-WWTR1:DVL2 [cytosol]
precedingEvent	[Reaction:R-CFA-2060328] Phosphorylation of WWTR1 (TAZ) by LATS1 - Canis familiaris [Reaction:R-CFA-2028661] Phosphorylation of WWTR1 (TAZ) by LATS2 - Canis familiaris
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-2066299
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-2028269] Signaling by Hippo
(inferredTo)	[Reaction:R-HSA-2066299] DVL2 binds phosphorylated WWTR1 (TAZ)

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