Reactome | Interaction of KIT and sSCF

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Interaction of KIT and sSCF Show undefined attributes

category	binding
compartment	[Compartment:876] plasma membrane [Compartment:984] extracellular region
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10246767
displayName	Interaction of KIT and sSCF
eventOf	[Pathway:R-CFA-1433557] Signaling by SCF-KIT - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-CFA-205231] Dimerization of KIT upon SCF binding - Canis familiaris
inferredFrom	[Reaction:R-HSA-205321] Interaction of KIT and sSCF - Homo sapiens
input	[EntityWithAccessionedSequence:R-CFA-197662] KIT [plasma membrane] [Complex:R-CFA-1433307] sSCF dimer [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	Interaction of KIT and sSCF
output	[Complex:R-CFA-205166] KIT:sSCF dimer [plasma membrane]
precedingEvent	[Reaction:R-CFA-1433395] Dimerization of sSCF - Canis familiaris
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-205321
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-1433557] Signaling by SCF-KIT
(precedingEvent)	[Reaction:R-CFA-205231] Dimerization of KIT upon SCF binding
(inferredTo)	[Reaction:R-HSA-205321] Interaction of KIT and sSCF

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