Reactome | G-protein activation

Schema > Pathway > Entries

G-protein activation Show undefined attributes

created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10329081
displayName	G-protein activation
eventOf	[Pathway:R-CFA-111885] Opioid Signalling - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-CFA-167408] The high affinity receptor complex binds to G-protein - Canis familiaris [Reaction:R-CFA-167419] The receptor:G-protein complex releases GDP - Canis familiaris [Reaction:R-CFA-167429] The receptor:G-protein complex binds GTP - Canis familiaris [Reaction:R-CFA-112271] The receptor:G-protein complex dissociates - Canis familiaris [Reaction:R-CFA-167415] G-protein alpha subunit is inactivated - Canis familiaris [Reaction:R-CFA-167433] G-protein beta-gamma subunits rebind the alpha-GDP subunit - Canis familiaris
inferredFrom	[Pathway:R-HSA-202040] G-protein activation - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	G-protein activation
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49646] Canis familiaris
stId	R-CFA-202040
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-111885] Opioid Signalling
(inferredTo)	[Pathway:R-HSA-202040] G-protein activation

© 2026 Reactome

Cite Us!