Reactome | The high affinity receptor complex binds to G-protein

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The high affinity receptor complex binds to G-protein Show undefined attributes

catalystActivity	[CatalystActivity:10238154] G protein-coupled receptor activity of Opioid:MOR [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10238156
displayName	The high affinity receptor complex binds to G-protein
eventOf	[Pathway:R-CFA-202040] G-protein activation - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-CFA-167419] The receptor:G-protein complex releases GDP - Canis familiaris
inferredFrom	[Reaction:R-HSA-167408] The high affinity receptor complex binds to G-protein - Homo sapiens
input	[Complex:R-CFA-167418] G protein-GDP complex [plasma membrane] [Complex:R-CFA-112039] Opioid:MOR [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	The high affinity receptor complex binds to G-protein
output	[Complex:R-CFA-167403] Opioid:MOR:G protein-GDP complex [plasma membrane]
precedingEvent	[Reaction:R-CFA-112042] Opioid binds MOR - Canis familiaris [Reaction:R-CFA-167433] G-protein beta-gamma subunits rebind the alpha-GDP subunit - Canis familiaris
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-167408
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-202040] G-protein activation
(precedingEvent)	[Reaction:R-CFA-167419] The receptor:G-protein complex releases GDP
(inferredTo)	[Reaction:R-HSA-167408] The high affinity receptor complex binds to G-protein

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