Reactome | phospho-RPS6KA5 [nucleoplasm]

Schema > EntityWithAccessionedSequence > Entries

catalystActivities	[CatalystActivity:10244131] protein serine/threonine kinase activity of p-S212,S360,S376,T581-RPS6KA5 [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10243311
displayName	phospho-RPS6KA5 [nucleoplasm]
endCoordinate	802
hasModifiedResidue	[ModifiedResidue:10243306] O-phospho-L-serine at 376 (in Homo sapiens) [ModifiedResidue:10243307] O-phospho-L-threonine at 581 (in Homo sapiens) [ModifiedResidue:10243308] O-phospho-L-serine at 360 (in Homo sapiens) [ModifiedResidue:10243309] O-phospho-L-serine at 212 (in Homo sapiens)
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-198683] p-S212,S360,S376,T581-RPS6KA5 [nucleoplasm] - Homo sapiens
maxDepth	1
name	phospho-RPS6KA5 p-S212,S360,S376,T581-RPS6KA5 A0A8I3S052
producedByEvent	[Reaction:R-CFA-198669] p38MAPK phosphorylates MSK1 - Canis familiaris [Reaction:R-CFA-198756] ERK1/2 phosphorylates MSK1 - Canis familiaris
referenceEntity	[ReferenceGeneProduct:uniprot:A0A8I3S052] UniProt:A0A8I3S052
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:49646] Canis familiaris
stId	R-CFA-198683
startCoordinate	1

(physicalEntity)	[CatalystActivity:10244131] protein serine/threonine kinase activity of p-S212,S360,S376,T581-RPS6KA5 [nucleoplasm]
(output)	[Reaction:R-CFA-198669] p38MAPK phosphorylates MSK1 [Reaction:R-CFA-198756] ERK1/2 phosphorylates MSK1
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-198683] p-S212,S360,S376,T581-RPS6KA5 [nucleoplasm]

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