Reactome | STING mediated induction of host immune responses

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STING mediated induction of host immune responses Show undefined attributes

created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10330893
displayName	STING mediated induction of host immune responses
eventOf	[Pathway:R-CFA-1834949] Cytosolic sensors of pathogen-associated DNA - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:259970] positive regulation of type I interferon production
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-CFA-9013869] DDX41 binds bacterial c-di-AMP, c-di-GMP - Canis familiaris [Pathway:R-CFA-3270619] IRF3-mediated induction of type I IFN - Canis familiaris [Pathway:R-CFA-3249367] STAT6-mediated induction of chemokines - Canis familiaris
inferredFrom	[Pathway:R-HSA-1834941] STING mediated induction of host immune responses - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	3
name	STING mediated induction of host immune responses
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49646] Canis familiaris
stId	R-CFA-1834941
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-1834949] Cytosolic sensors of pathogen-associated DNA
(inferredTo)	[Pathway:R-HSA-1834941] STING mediated induction of host immune responses

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