Reactome | Polymerase switching on the C-strand of the telomere

Schema > Pathway > Entries

Polymerase switching on the C-strand of the telomere Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10329553
displayName	Polymerase switching on the C-strand of the telomere
eventOf	[Pathway:R-CFA-174417] Telomere C-strand (Lagging Strand) Synthesis - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Pathway:R-CFA-174414] Processive synthesis on the C-strand of the telomere - Canis familiaris
goBiologicalProcess	[GO_BiologicalProcess:263978] telomere maintenance via semi-conservative replication
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-CFA-174452] RFC binding displaces Pol Alpha on the C-strand of the telomere - Canis familiaris [Reaction:R-CFA-174439] Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere - Canis familiaris [Reaction:R-CFA-174447] RFC dissociates after sliding clamp formation on the C-strand of the telomere - Canis familiaris [Reaction:R-CFA-174448] Formation of Processive Complex on the C-strand of the telomere - Canis familiaris
inferredFrom	[Pathway:R-HSA-174411] Polymerase switching on the C-strand of the telomere - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Polymerase switching on the C-strand of the telomere
precedingEvent	[Pathway:R-CFA-174430] Telomere C-strand synthesis initiation - Canis familiaris
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49646] Canis familiaris
stId	R-CFA-174411
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-174417] Telomere C-strand (Lagging Strand) Synthesis
(precedingEvent)	[Pathway:R-CFA-174414] Processive synthesis on the C-strand of the telomere
(inferredTo)	[Pathway:R-HSA-174411] Polymerase switching on the C-strand of the telomere

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