Reactome | Signalling to RAS

Schema > Pathway > Entries

created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10329479
displayName	Signalling to RAS
eventOf	[Pathway:R-CFA-187687] Signalling to ERKs - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:20313] Ras protein signal transduction
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-CFA-5685366] GRB2-1:SOS1 binds p-Y-SHC - Canis familiaris [Pathway:R-CFA-171007] p38MAPK events - Canis familiaris
inferredFrom	[Pathway:R-HSA-167044] Signalling to RAS - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	3
name	Signalling to RAS
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49646] Canis familiaris
stId	R-CFA-167044
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-CFA-187687] Signalling to ERKs
(inferredTo)	[Pathway:R-HSA-167044] Signalling to RAS

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