Reactome | uPAR-acyl-GPI + H2O -> uPAR + long-chain fatty acid

Schema > Reaction > Entries

uPAR-acyl-GPI + H2O -> uPAR + long-chain fatty acid Show undefined attributes

catalystActivity	[CatalystActivity:10236839] hydrolase activity, acting on ester bonds of PGAP1 [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:17957] endoplasmic reticulum lumen [Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10236841
displayName	uPAR-acyl-GPI + H2O -> uPAR + long-chain fatty acid
eventOf	[Pathway:R-CFA-162791] Attachment of GPI anchor to uPAR - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-162729] uPAR-acyl-GPI + H2O -> uPAR + long-chain fatty acid - Homo sapiens
input	[EntityWithAccessionedSequence:R-CFA-162687] GPI-PLAUR [endoplasmic reticulum membrane] [SimpleEntity:R-ALL-113519] H2O [endoplasmic reticulum lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	uPAR-acyl-GPI + H2O -> uPAR + long-chain fatty acid
output	[SimpleEntity:R-ALL-1524021] LCFA(-) [endoplasmic reticulum membrane] [EntityWithAccessionedSequence:R-CFA-162703] PLAUR [endoplasmic reticulum membrane]
precedingEvent	[Reaction:R-CFA-162836] uPAR precursor + acyl-GPI -> uPAR-acyl-GPI + uPAR propeptide - Canis familiaris
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-162729
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-162791] Attachment of GPI anchor to uPAR
(inferredTo)	[Reaction:R-HSA-162729] uPAR-acyl-GPI + H2O -> uPAR + long-chain fatty acid

Cite Us!