Reactome | Processive elongation complex [nucleoplasm]

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Processive elongation complex [nucleoplasm]

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compartment	[Compartment:7660] nucleoplasm
consumedByEvent	[Reaction:R-CFA-113414] 7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest - Canis familiaris [Reaction:R-CFA-113413] TFIIS-mediated recovery of elongation from arrest - Canis familiaris [Reaction:R-CFA-113412] Pol II elongation complex moves on the template as transcript elongates - Canis familiaris [Reaction:R-CFA-112395] Abortive termination of elongation after arrest - Canis familiaris [Reaction:R-CFA-113411] 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing - Canis familiaris [Reaction:R-CFA-113429] Elongating transcript encounters a lesion in the template - Canis familiaris
created	[InstanceEdit:9933613] Shorser, Solomon, 2020-11-19
dbId	9941811
displayName	Processive elongation complex [nucleoplasm]
hasComponent	[EntityWithAccessionedSequence:R-CFA-8932788] AFF4 [nucleoplasm] [EntityWithAccessionedSequence:R-CFA-113416] CTDP1 [nucleoplasm] [Complex:R-CFA-112420] DSIF complex [nucleoplasm] [EntityWithAccessionedSequence:R-CFA-8932787] EAF1 [nucleoplasm] [EntityWithAccessionedSequence:R-CFA-8932790] EAF2 [nucleoplasm] [EntityWithAccessionedSequence:R-CFA-54257] ELL [nucleoplasm] [OtherEntity:R-ALL-113717] Elongating transcript in processive Pol II mediated elongation [nucleoplasm] [Complex:R-CFA-112425] Elongin Complex [nucleoplasm] [Complex:R-CFA-112417] FACT complex [nucleoplasm] [EntityWithAccessionedSequence:R-CFA-8932911] IWS1 [nucleoplasm] [EntityWithAccessionedSequence:R-CFA-8932918] MLLT1 [nucleoplasm] [EntityWithAccessionedSequence:R-CFA-8932789] MLLT3 [nucleoplasm] [Complex:R-CFA-112432] NELF complex [nucleoplasm] [DefinedSet:R-ALL-30595] NTP [nucleoplasm] [Complex:R-CFA-112431] P-TEFb complex [nucleoplasm] [Complex:R-CFA-8866690] PAF1C [nucleoplasm] [Complex:R-CFA-113425] RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] [EntityWithAccessionedSequence:R-CFA-8932908] SUPT6H [nucleoplasm] [EntityWithAccessionedSequence:R-CFA-65748] TCEA1 [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-113721] Arrested processive elongation complex [nucleoplasm] - Homo sapiens [Complex:R-HSA-113719] Processive elongation complex [nucleoplasm] - Homo sapiens
name	Processive elongation complex
producedByEvent	[Reaction:R-CFA-113414] 7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest - Canis familiaris [Reaction:R-CFA-112385] Addition of nucleotides leads to transcript elongation - Canis familiaris [Reaction:R-CFA-112392] Resumption of elongation after recovery from pausing - Canis familiaris [Reaction:R-CFA-113413] TFIIS-mediated recovery of elongation from arrest - Canis familiaris
schemaClass	Complex
species	[Species:49646] Canis familiaris
stId	R-CFA-113719
summation	[Summation:9707412] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Referrals

(input)	[Reaction:R-CFA-113429] Elongating transcript encounters a lesion in the template - Canis familiaris [Reaction:R-CFA-112395] Abortive termination of elongation after arrest - Canis familiaris [Reaction:R-CFA-113412] Pol II elongation complex moves on the template as transcript elongates - Canis familiaris [Reaction:R-CFA-113413] TFIIS-mediated recovery of elongation from arrest - Canis familiaris [Reaction:R-CFA-113414] 7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest - Canis familiaris [Reaction:R-CFA-113411] 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing - Canis familiaris
(output)	[Reaction:R-CFA-113413] TFIIS-mediated recovery of elongation from arrest - Canis familiaris [Reaction:R-CFA-113414] 7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest - Canis familiaris [Reaction:R-CFA-112392] Resumption of elongation after recovery from pausing - Canis familiaris [Reaction:R-CFA-112385] Addition of nucleotides leads to transcript elongation - Canis familiaris
(inferredTo)	[Complex:R-HSA-113721] Arrested processive elongation complex [nucleoplasm] - Homo sapiens [Complex:R-HSA-113719] Processive elongation complex [nucleoplasm] - Homo sapiens

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