Reactome | AP2 binds chlorpromazine

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10988374
displayName	AP2 binds chlorpromazine
eventOf	[Pathway:R-CEL-8856825] Cargo recognition for clathrin-mediated endocytosis - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9681616] AP2 binds chlorpromazine - Homo sapiens
input	[Complex:R-CEL-167712] AP-2 Complex [cytosol] [ChemicalDrug:R-ALL-9648300] chlorpromazine [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	AP2 binds chlorpromazine
output	[Complex:R-CEL-9681612] AP2:chlorpromazine [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-9681616
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-CEL-8856825] Cargo recognition for clathrin-mediated endocytosis
(inferredTo)	[Reaction:R-HSA-9681616] AP2 binds chlorpromazine

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