Reactome | phospho-pS181-S-Farn-Me KRAS4B [plasma membrane]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:876] plasma membrane
consumedByEvent	[BlackBoxEvent:R-CEL-9653592] pS181-S-Farn-Me KRAS4B translocates to the outer mitochondrial membrane - Caenorhabditis elegans
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10988139
displayName	phospho-pS181-S-Farn-Me KRAS4B [plasma membrane]
endCoordinate	186
hasModifiedResidue	[ModifiedResidue:10924221] S-farnesyl-L-cysteine methyl ester at 185 (in Homo sapiens) [ModifiedResidue:10988137] O-phospho-L-serine at 181 (in Homo sapiens)
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-9653482] pS181-S-Farn-Me KRAS4B [plasma membrane] - Homo sapiens
maxDepth	1
name	phospho-pS181-S-Farn-Me KRAS4B P22981
negativelyRegulates	[NegativeRegulation:10988156] Negative regulation by 'pS181-S-Farn-Me KRAS4B [plasma membrane]'
producedByEvent	[Reaction:R-CEL-9653503] KRAS4B is phosphorylated on serine 181 - Caenorhabditis elegans
referenceEntity	[ReferenceGeneProduct:uniprot:P22981] UniProt:P22981
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-9653482
startCoordinate	1

(input)	[BlackBoxEvent:R-CEL-9653592] pS181-S-Farn-Me KRAS4B translocates to the outer mitochondrial membrane
(output)	[Reaction:R-CEL-9653503] KRAS4B is phosphorylated on serine 181
(regulator)	[NegativeRegulation:10988156] Negative regulation by 'pS181-S-Farn-Me KRAS4B [plasma membrane]'
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-9653482] pS181-S-Farn-Me KRAS4B [plasma membrane]

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