Reactome | RUNX3 regulates CDKN1A transcription

Schema > Pathway > Entries

created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10995785
displayName	RUNX3 regulates CDKN1A transcription
eventOf	[Pathway:R-CEL-8878159] Transcriptional regulation by RUNX3 - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-CEL-8878143] RUNX3 binds SMAD3 and SMAD4 - Caenorhabditis elegans [BlackBoxEvent:R-CEL-8878117] RUNX3 binds ZFHX3 - Caenorhabditis elegans
inferredFrom	[Pathway:R-HSA-8941855] RUNX3 regulates CDKN1A transcription - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	RUNX3 regulates CDKN1A transcription
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-8941855
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-CEL-8878159] Transcriptional regulation by RUNX3
(inferredTo)	[Pathway:R-HSA-8941855] RUNX3 regulates CDKN1A transcription

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