Reactome | Phosphorylation (Ser5) of RNA pol II CTD

Schema > Reaction > Entries

Phosphorylation (Ser5) of RNA pol II CTD Show undefined attributes

catalystActivity	[CatalystActivity:10920397] protein serine/threonine kinase activity of Pol II transcription complex containing extruded transcript to +30 [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10920399
displayName	Phosphorylation (Ser5) of RNA pol II CTD
eventOf	[Pathway:R-CEL-77075] RNA Pol II CTD phosphorylation and interaction with CE - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-CEL-77069] RNA Polymerase II CTD (phosphorylated) binds to CE - Caenorhabditis elegans
inferredFrom	[Reaction:R-HSA-77071] Phosphorylation (Ser5) of RNA pol II CTD - Homo sapiens
input	13 × [SimpleEntity:R-ALL-29358] ATP [nucleoplasm] [Complex:R-CEL-157171] Pol II transcription complex containing extruded transcript to +30 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	Phosphorylation (Ser5) of RNA pol II CTD
output	13 × [SimpleEntity:R-ALL-113582] ADP [nucleoplasm] [Complex:R-CEL-157174] Pol II transcription complex with (ser5) phosphorylated CTD containing extruded transcript to +30 [nucleoplasm]
precedingEvent	[Reaction:R-CEL-113430] Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex - Caenorhabditis elegans
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-77071
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CEL-77075] RNA Pol II CTD phosphorylation and interaction with CE
(precedingEvent)	[Reaction:R-CEL-77069] RNA Polymerase II CTD (phosphorylated) binds to CE
(inferredTo)	[Reaction:R-HSA-77071] Phosphorylation (Ser5) of RNA pol II CTD