Reactome | gcsh-2 [mitochondrial matrix]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:5460] mitochondrial matrix
consumedByEvent	[Reaction:R-CEL-6792572] LIPT1 transfers lipoyl group from lipoyl-GCSH to DBT/DLST - Caenorhabditis elegans [Reaction:R-CEL-9858752] LIPT1 transfers lipoyl group from lipoyl-GCSH to DLAT - Caenorhabditis elegans [Reaction:R-CEL-9858752] LIPT1 transfers lipoyl group from lipoyl-GCSH to DLAT - Caenorhabditis elegans [Reaction:R-CEL-5693967] PXLP-K754-GLDC dimer decarboxylates Gly - Caenorhabditis elegans
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10971111
displayName	gcsh-2 [mitochondrial matrix]
endCoordinate	173
hasModifiedResidue	[ModifiedResidue:10971109] N6-lipoyl-L-lysine at 107 (in Homo sapiens)
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-6793611] Lipo-K107-GCSH [mitochondrial matrix] - Homo sapiens
maxDepth	1
name	gcsh-2 Lipo-K107-GCSH Q20634
producedByEvent	[Reaction:R-CEL-5694018] DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate - Caenorhabditis elegans
referenceEntity	[ReferenceGeneProduct:uniprot:Q20634] UniProt:Q20634
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-6793611
startCoordinate	49

(input)	[Reaction:R-CEL-6792572] LIPT1 transfers lipoyl group from lipoyl-GCSH to DBT/DLST [Reaction:R-CEL-9858752] LIPT1 transfers lipoyl group from lipoyl-GCSH to DLAT [Reaction:R-CEL-5693967] PXLP-K754-GLDC dimer decarboxylates Gly
(output)	[Reaction:R-CEL-5694018] DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-6793611] Lipo-K107-GCSH [mitochondrial matrix]

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