Reactome | RHO GTPases Activate Rhotekin and Rhophilins

Schema > Pathway > Entries

created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10995537
displayName	RHO GTPases Activate Rhotekin and Rhophilins
eventOf	[Pathway:R-CEL-195258] RHO GTPase Effectors - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-CEL-5666197] RHOA:GTP:RTKN binds LIN7B - Caenorhabditis elegans
inferredFrom	[Pathway:R-HSA-5666185] RHO GTPases Activate Rhotekin and Rhophilins - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	RHO GTPases Activate Rhotekin and Rhophilins
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-5666185
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-CEL-195258] RHO GTPase Effectors
(inferredTo)	[Pathway:R-HSA-5666185] RHO GTPases Activate Rhotekin and Rhophilins

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