Reactome | Phospholipase C-mediated cascade: FGFR1

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Phospholipase C-mediated cascade: FGFR1 Show undefined attributes

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10995491
displayName	Phospholipase C-mediated cascade: FGFR1
eventOf	[Pathway:R-CEL-5654687] Downstream signaling of activated FGFR1 - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-CEL-5654167] Activated FGFR1 binds PLCG1 - Caenorhabditis elegans [Reaction:R-CEL-5654149] Activated FGFR1 phosphorylates PLCG1 - Caenorhabditis elegans [Reaction:R-CEL-5654165] p-4Y-PLCG1 dissociates from activated FGFR1 - Caenorhabditis elegans
inferredFrom	[Pathway:R-HSA-5654219] Phospholipase C-mediated cascade: FGFR1 - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Phospholipase C-mediated cascade: FGFR1
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-5654219
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CEL-5654687] Downstream signaling of activated FGFR1
(inferredTo)	[Pathway:R-HSA-5654219] Phospholipase C-mediated cascade: FGFR1

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