Reactome | MeSeOH is reduced to MeSeH by TXNRD1

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MeSeOH is reduced to MeSeH by TXNRD1 Show undefined attributes

catalystActivity	[CatalystActivity:10964684] methylselenol reductase activity of TNXRD1:FAD dimer [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10964686
displayName	MeSeOH is reduced to MeSeH by TXNRD1
eventOf	[Pathway:R-CEL-5263617] Metabolism of ingested MeSeO2H into MeSeH - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5263614] MeSeOH is reduced to MeSeH by TXNRD1 - Homo sapiens
input	[SimpleEntity:R-ALL-70106] H+ [cytosol] [SimpleEntity:R-ALL-5357663] MeSeOH [cytosol] [SimpleEntity:R-ALL-29364] NADPH [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	MeSeOH is reduced to MeSeH by TXNRD1
output	[SimpleEntity:R-ALL-29356] H2O [cytosol] [SimpleEntity:R-ALL-5357669] MeSeH [cytosol] [SimpleEntity:R-ALL-29366] NADP+ [cytosol]
precedingEvent	[Reaction:R-CEL-5263616] MeSeO2H is reduced to MeSeOH by TXNRD1 - Caenorhabditis elegans
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-5263614
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CEL-5263617] Metabolism of ingested MeSeO2H into MeSeH
(inferredTo)	[Reaction:R-HSA-5263614] MeSeOH is reduced to MeSeH by TXNRD1

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