Reactome | (d)NDP + ATP <=> (d)NTP + ADP (NME4)

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(d)NDP + ATP <=> (d)NTP + ADP (NME4) Show undefined attributes

catalystActivity	[CatalystActivity:10940779] nucleoside diphosphate kinase activity of NME4 hexamer [mitochondrial inner membrane]
category	transition
compartment	[Compartment:5460] mitochondrial matrix [Compartment:70616] mitochondrial inner membrane
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10940781
displayName	(d)NDP + ATP <=> (d)NTP + ADP (NME4)
eventOf	[Pathway:R-CEL-499943] Interconversion of nucleotide di- and triphosphates - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-482804] (d)NDP + ATP <=> (d)NTP + ADP (NME4) - Homo sapiens
input	[DefinedSet:R-ALL-482803] (d)NDP [mitochondrial matrix] [SimpleEntity:R-ALL-113593] ATP [mitochondrial matrix]
isInDisease	false
isInferred	true
maxDepth	1
name	(d)NDP + ATP <=> (d)NTP + ADP (NME4) GDP + ATP => GTP + ADP CDP + ATP => CTP + ADP UDP + ATP => UTP + ADP dADP + ATP => dATP + ADP dGDP + ATP => dGTP + ADP dCDP + ATP => dCTP + ADP dTDP + ATP => dTTP + ADP dUDP + ATP => dUTP + ADP
output	[DefinedSet:R-ALL-482807] (d)NTP [mitochondrial matrix] [SimpleEntity:R-ALL-113581] ADP [mitochondrial matrix]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-482804
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CEL-499943] Interconversion of nucleotide di- and triphosphates
(inferredTo)	[Reaction:R-HSA-482804] (d)NDP + ATP <=> (d)NTP + ADP (NME4)

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