Reactome | pix-1 [cytosol]

Schema > EntityWithAccessionedSequence > Entries

candidateOf	[CandidateSet:R-CEL-8980694] RHOA GEFs [cytosol] - Caenorhabditis elegans [CandidateSet:R-CEL-9020366] RHOV effectors [cytosol] - Caenorhabditis elegans [CandidateSet:R-CEL-9013242] CDC42 effectors [cytosol] - Caenorhabditis elegans
compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-CEL-3928512] EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] - Caenorhabditis elegans [Complex:R-CEL-182917] Beta-Pix:CDC42:GTP [cytosol] - Caenorhabditis elegans [Complex:R-CEL-182915] Ub-Beta-Pix:CDC42:GTP [cytosol] - Caenorhabditis elegans
consumedByEvent	[Reaction:R-CEL-3928631] GIT1 binds bPIX - Caenorhabditis elegans
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10924995
displayName	pix-1 [cytosol]
endCoordinate	803
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-430346] ARHGEF7 [cytosol] - Homo sapiens
maxDepth	1
name	pix-1 ARHGEF7 Q21430
referenceEntity	[ReferenceGeneProduct:uniprot:Q21430] UniProt:Q21430
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-430346
startCoordinate	1

(hasCandidate)	[CandidateSet:R-CEL-8980694] RHOA GEFs [cytosol] [CandidateSet:R-CEL-9020366] RHOV effectors [cytosol] [CandidateSet:R-CEL-9018845] RHOQ effectors [cytosol] [CandidateSet:R-CEL-9013242] CDC42 effectors [cytosol] [CandidateSet:R-CEL-9017506] RHOJ effectors [cytosol]
(activeUnit)	[CatalystActivity:10961864] guanyl-nucleotide exchange factor activity of EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane]
(input)	[Reaction:R-CEL-3928631] GIT1 binds bPIX
(hasComponent)	[Complex:R-CEL-3928512] EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] [Complex:R-CEL-182915] Ub-Beta-Pix:CDC42:GTP [cytosol] [Complex:R-CEL-182917] Beta-Pix:CDC42:GTP [cytosol]
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-430346] ARHGEF7 [cytosol]