Reactome | ACOX1 oxidizes C26:0 CoA

Schema > Reaction > Entries

ACOX1 oxidizes C26:0 CoA Show undefined attributes

catalystActivity	[CatalystActivity:10934862] acyl-CoA oxidase activity of ACOX1 dimer [peroxisomal matrix]
category	transition
compartment	[Compartment:17951] peroxisomal matrix
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10934864
displayName	ACOX1 oxidizes C26:0 CoA
eventOf	[Pathway:R-CEL-390247] Beta-oxidation of very long chain fatty acids - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-CEL-390252] HSD17B4 hydrates trans-2,3-dehydrohexacosanoyl-CoA - Caenorhabditis elegans
inferredFrom	[Reaction:R-HSA-390256] ACOX1 oxidizes C26:0 CoA - Homo sapiens
input	[SimpleEntity:R-ALL-390260] C26:0 CoA [peroxisomal matrix] [SimpleEntity:R-ALL-113535] O2 [peroxisomal matrix]
isInDisease	false
isInferred	true
maxDepth	1
name	ACOX1 oxidizes C26:0 CoA hexacosanoyl-CoA + O2 => (2E)-hexacosenoyl-CoA + H2O2
output	[SimpleEntity:R-ALL-113575] H2O2 [peroxisomal matrix] [SimpleEntity:R-ALL-390249] trans-2,3-dehydrohexacosanoyl-CoA [peroxisomal matrix]
precedingEvent	[Reaction:R-CEL-9914143] SLC27A2-mediated ligation of peroxisomal fatty acid and CoASH - Caenorhabditis elegans
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-390256
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CEL-390247] Beta-oxidation of very long chain fatty acids
(precedingEvent)	[Reaction:R-CEL-390252] HSD17B4 hydrates trans-2,3-dehydrohexacosanoyl-CoA
(inferredTo)	[Reaction:R-HSA-390256] ACOX1 oxidizes C26:0 CoA

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