Reactome | SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine

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SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine Show undefined attributes

catalystActivity	[CatalystActivity:10931699] amino acid transmembrane transporter activity of SLC1A4 [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10931707
displayName	SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine
eventOf	[Pathway:R-CEL-352230] Amino acid transport across the plasma membrane - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-352371] SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine - Homo sapiens
input	[DefinedSet:R-ALL-352355] alanine, serine, threonine, or cysteine [cytosol] [SimpleEntity:R-ALL-352000] L-Thr [extracellular region] [SimpleEntity:R-ALL-83910] Na+ [cytosol] [SimpleEntity:R-ALL-74113] Na+ [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine
output	[DefinedSet:R-ALL-352359] alanine, serine, threonine, or cysteine [extracellular region] [SimpleEntity:R-ALL-351990] L-Thr [cytosol] [SimpleEntity:R-ALL-83910] Na+ [cytosol] [SimpleEntity:R-ALL-74113] Na+ [extracellular region]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-352371
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CEL-352230] Amino acid transport across the plasma membrane
(inferredTo)	[Reaction:R-HSA-352371] SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine

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