Reactome | SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine

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SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine Show undefined attributes

authored	[InstanceEdit:352382] D'Eustachio, P, 2008-06-02 20:10:30
catalystActivity	[CatalystActivity:352361] amino acid transmembrane transporter activity of SLC1A4 [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:352351] D'Eustachio, P, 2008-06-02 18:13:12
crossReference	[DatabaseIdentifier:11879967] Rhea:69999
dbId	352371
displayName	SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine
edited	[InstanceEdit:352382] D'Eustachio, P, 2008-06-02 20:10:30
eventOf	[Pathway:R-HSA-352230] Amino acid transport across the plasma membrane - Homo sapiens
input	[DefinedSet:R-ALL-352355] alanine, serine, threonine, or cysteine [cytosol] [SimpleEntity:R-ALL-352000] L-Thr [extracellular region] [SimpleEntity:R-ALL-83910] Na+ [cytosol] [SimpleEntity:R-ALL-74113] Na+ [extracellular region]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:352345] ASCT-1 is a neutral amino acid exchanger with chloride channel activity [LiteratureReference:352362] Cloning and expression of a human neutral amino acid transporter with structural similarity to the glutamate transporter gene family [LiteratureReference:352348] Cloning and expression of a novel Na(+)-dependent neutral amino acid transporter structurally related to mammalian Na+/glutamate cotransporters
modified	[InstanceEdit:11879863] Wright, Adam, 2024-03-11
name	SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine
orthologousEvent	[Reaction:R-CEL-352371] SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine - Caenorhabditis elegans [Reaction:R-DME-352371] SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine - Drosophila melanogaster [Reaction:R-GGA-352371] SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine - Gallus gallus [Reaction:R-XTR-352371] SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine - Xenopus tropicalis [Reaction:R-DRE-352371] SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine - Danio rerio [Reaction:R-SSC-352371] SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine - Sus scrofa [Reaction:R-BTA-352371] SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine - Bos taurus [Reaction:R-CFA-352371] SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine - Canis familiaris [Reaction:R-RNO-352371] SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine - Rattus norvegicus [Reaction:R-MMU-352371] SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine - Mus musculus
output	[DefinedSet:R-ALL-352359] alanine, serine, threonine, or cysteine [extracellular region] [SimpleEntity:R-ALL-351990] L-Thr [cytosol] [SimpleEntity:R-ALL-83910] Na+ [cytosol] [SimpleEntity:R-ALL-74113] Na+ [extracellular region]
releaseDate	2008-06-30
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:352498] Jassal, Bijay, 2008-06-03
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-352371
summation	[Summation:352373] SLC1A4, associated with the plasma membrane, mediates the ex...

Referrals

(hasEvent)

[Pathway:R-HSA-352230] Amino acid transport across the plasma membrane