Reactome | WLS is endocytosed to the early endosome

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WLS is endocytosed to the early endosome Show undefined attributes

category	omitted
compartment	[Compartment:171062] early endosome membrane [Compartment:876] plasma membrane
created	[InstanceEdit:10740525] Wright, Adam, 2024-03-08
dbId	10785502
displayName	WLS is endocytosed to the early endosome
eventOf	[Pathway:R-CEL-3238698] WNT ligand biogenesis and trafficking - Caenorhabditis elegans
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[Reaction:R-CEL-3247839] Retromer associates with WLS - Caenorhabditis elegans
inferredFrom	[BlackBoxEvent:R-HSA-3247847] WLS is endocytosed to the early endosome - Homo sapiens
input	[EntityWithAccessionedSequence:R-CEL-3247746] mig-14 [plasma membrane]
isInDisease	false
isInferred	true
name	WLS is endocytosed to the early endosome
output	[EntityWithAccessionedSequence:R-CEL-3247745] mig-14 [early endosome membrane]
precedingEvent	[Reaction:R-CEL-3247843] secretion of WNT ligands - Caenorhabditis elegans
releaseDate	2024-03-27
schemaClass	BlackBoxEvent
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-3247847
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CEL-3238698] WNT ligand biogenesis and trafficking
(precedingEvent)	[Reaction:R-CEL-3247839] Retromer associates with WLS
(inferredTo)	[BlackBoxEvent:R-HSA-3247847] WLS is endocytosed to the early endosome