Reactome | Abacavir metabolism

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Abacavir metabolism Show undefined attributes

created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10995175
displayName	Abacavir metabolism
eventOf	[Pathway:R-CEL-2161522] Abacavir ADME - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:8764] xenobiotic metabolic process
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-CEL-2162078] abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ - Caenorhabditis elegans [Reaction:R-CEL-2161195] abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine - Caenorhabditis elegans [Reaction:R-CEL-2162066] carbovir + IMP => carbovir monophosphate + inosine - Caenorhabditis elegans
inferredFrom	[Pathway:R-HSA-2161541] Abacavir metabolism - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Abacavir metabolism
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-2161541
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CEL-2161522] Abacavir ADME
(inferredTo)	[Pathway:R-HSA-2161541] Abacavir metabolism

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