Reactome | abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine

Schema > Reaction > Entries

abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine Show undefined attributes

catalystActivity	[CatalystActivity:10956316] N6-methyl-AMP deaminase activity of MAPDA:Zn [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10956320
displayName	abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine
eventOf	[Pathway:R-CEL-2161541] Abacavir metabolism - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-2161195] abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine - Homo sapiens
input	[ChemicalDrug:R-ALL-2161194] abacavir monophosphate [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine Deamination of abacavir monophosphate to form carbovir monophosphate
output	[ChemicalDrug:R-ALL-2161176] carbovir monophosphate [cytosol] [SimpleEntity:R-ALL-2161175] cyclopropylamine [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-2161195
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CEL-2161541] Abacavir metabolism
(inferredTo)	[Reaction:R-HSA-2161195] abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine

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