Reactome | NAGLU hydrolyses heparan chain(2)

Schema > Reaction > Entries

NAGLU hydrolyses heparan chain(2) Show undefined attributes

catalystActivity	[CatalystActivity:10777445] alpha-N-acetylglucosaminidase activity of NAGLU(59-743) [lysosomal lumen]
category	transition
compartment	[Compartment:161320] lysosomal lumen
created	[InstanceEdit:10740525] Wright, Adam, 2024-03-08
dbId	10781559
displayName	NAGLU hydrolyses heparan chain(2)
eventOf	[Pathway:R-CEL-2024096] HS-GAG degradation - Caenorhabditis elegans
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[Reaction:R-CEL-1678854] GUSB tetramer hydrolyses CS/HS precursor - Caenorhabditis elegans
inferredFrom	[Reaction:R-HSA-2090038] NAGLU hydrolyses heparan chain(2) - Homo sapiens
input	[SimpleEntity:R-ALL-1605715] H2O [lysosomal lumen] [SimpleEntity:R-ALL-2090053] Heparan chain(2) [lysosomal lumen]
isInDisease	false
isInferred	true
name	NAGLU hydrolyses heparan chain(2)
output	[SimpleEntity:R-ALL-2065212] CS/HS precursor [lysosomal lumen] [SimpleEntity:R-ALL-1678743] GlcNAc [lysosomal lumen]
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-2090038
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CEL-2024096] HS-GAG degradation
(precedingEvent)	[Reaction:R-CEL-1678854] GUSB tetramer hydrolyses CS/HS precursor
(inferredTo)	[Reaction:R-HSA-2090038] NAGLU hydrolyses heparan chain(2)