Reactome | Phosphorylation of STK3 (MST2) and SAV1 by STK3

Schema > Reaction > Entries

Phosphorylation of STK3 (MST2) and SAV1 by STK3 Show undefined attributes

catalystActivity	[CatalystActivity:10954700] protein serine/threonine kinase activity of STK3:SAV1 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10954702
displayName	Phosphorylation of STK3 (MST2) and SAV1 by STK3
eventOf	[Pathway:R-CEL-2028269] Signaling by Hippo - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-CEL-2028589] Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) - Caenorhabditis elegans [Reaction:R-CEL-2028635] Phosphorylation of MOB1A and B by p-STK3 (p-MST2) - Caenorhabditis elegans
inferredFrom	[Reaction:R-HSA-2028591] Phosphorylation of STK3 (MST2) and SAV1 by STK3 - Homo sapiens
input	4 × [SimpleEntity:R-ALL-113592] ATP [cytosol] [Complex:R-CEL-2028275] STK3:SAV1 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Phosphorylation of STK3 (MST2) and SAV1 by STK3
output	4 × [SimpleEntity:R-ALL-29370] ADP [cytosol] [Complex:R-CEL-2028261] p-STK3:p-SAV1 [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-2028591
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CEL-2028269] Signaling by Hippo
(precedingEvent)	[Reaction:R-CEL-2028589] Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) [Reaction:R-CEL-2028635] Phosphorylation of MOB1A and B by p-STK3 (p-MST2)
(inferredTo)	[Reaction:R-HSA-2028591] Phosphorylation of STK3 (MST2) and SAV1 by STK3

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