Reactome | Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2

Schema > Reaction > Entries

Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2 Show undefined attributes

catalystActivity	[CatalystActivity:10914337] cyclin-dependent protein serine/threonine kinase activity of CCNA:p-T160-CDK2 [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10925915
displayName	Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2
eventOf	[Pathway:R-CEL-69656] Cyclin A:Cdk2-associated events at S phase entry - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-187948] Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2 - Homo sapiens
input	[SimpleEntity:R-ALL-29358] ATP [nucleoplasm] [DefinedSet:R-CEL-187963] FZR1,p-S795-RB1 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2
output	[SimpleEntity:R-ALL-113582] ADP [nucleoplasm] [DefinedSet:R-CEL-187920] p-FZR1,p-RB1 [nucleoplasm]
precedingEvent	[Reaction:R-CEL-187949] CAK-mediated phosphorylation of Cyclin A:Cdk2 - Caenorhabditis elegans
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-187948
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CEL-69656] Cyclin A:Cdk2-associated events at S phase entry
(inferredTo)	[Reaction:R-HSA-187948] Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2

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