Reactome | ISGylation of protein translation regulator 4EHP

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ISGylation of protein translation regulator 4EHP Show undefined attributes

category	dissociation
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10951627
displayName	ISGylation of protein translation regulator 4EHP
eventOf	[Pathway:R-CEL-1169408] ISG15 antiviral mechanism - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-1678843] ISGylation of protein translation regulator 4EHP - Homo sapiens
input	[EntityWithAccessionedSequence:R-CEL-1678822] ife-4 [cytosol] [Complex:R-CEL-9968643] ISG15:UBCH8:ARIH1 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	ISGylation of protein translation regulator 4EHP
output	[EntityWithAccessionedSequence:R-CEL-1678825] ARIH1 [cytosol] [Complex:R-CEL-1678834] ISGylated 4EHP [cytosol] [EntityWithAccessionedSequence:R-CEL-936014] ubc-18 [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-1678843
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CEL-1169408] ISG15 antiviral mechanism
(inferredTo)	[Reaction:R-HSA-1678843] ISGylation of protein translation regulator 4EHP

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