Reactome | Nuclear Pore Complex (NPC) [nuclear envelope]

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Nuclear Pore Complex (NPC) [nuclear envelope] Show undefined attributes

catalystActivities	[CatalystActivity:10962596] SUMO transferase activity of Nuclear Pore Complex (NPC) [nuclear envelope] [CatalystActivity:10964652] structural constituent of nuclear pore activity of Nuclear Pore Complex (NPC) [nuclear envelope] [CatalystActivity:10951769] narrow pore channel activity of Nuclear Pore Complex (NPC) [nuclear envelope]
compartment	[Compartment:13231] nuclear envelope
componentOf	[Complex:R-CEL-113815] NPC:NXF1,2:NXT1:EJC:CBC:mRNA [nucleoplasm] - Caenorhabditis elegans
consumedByEvent	[Reaction:R-CEL-2990882] CDK1 phosphorylates NUP98 - Caenorhabditis elegans
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10919185
displayName	Nuclear Pore Complex (NPC) [nuclear envelope]
hasComponent	8 × [GenomeEncodedEntity:R-CEL-157738] Ghost homologue of AAAS [nuclear envelope] 16 × [GenomeEncodedEntity:R-CEL-157752] Ghost homologue of NUP188 [nuclear envelope] 32 × [GenomeEncodedEntity:R-CEL-157753] Ghost homologue of NUP88 [cytosol] 16 × [GenomeEncodedEntity:R-CEL-157697] Ghost homologue of NUPL2 [cytosol] 8 × [GenomeEncodedEntity:R-CEL-157703] Ghost homologue of RANBP2 [cytosol] 8 × [EntityWithAccessionedSequence:R-CEL-2990912] npp-10 [nuclear envelope] 16 × [EntityWithAccessionedSequence:R-CEL-157722] npp-12 [nuclear envelope] 8 × [EntityWithAccessionedSequence:R-CEL-157691] npp-14 [cytosol] 16 × [EntityWithAccessionedSequence:R-CEL-157747] npp-14 [nuclear envelope] 32 × [EntityWithAccessionedSequence:R-CEL-157740] npp-16 [nucleoplasm] 16 × [EntityWithAccessionedSequence:R-CEL-157750] npp-18 [nuclear envelope] 16 × [EntityWithAccessionedSequence:R-CEL-157692] npp-21 [nucleoplasm] 32 × [EntityWithAccessionedSequence:R-CEL-6805183] npp-22 [nuclear envelope] 8 × [EntityWithAccessionedSequence:R-CEL-157695] npp-7 [nucleoplasm] 32 × [Complex:R-CEL-377883] Nup107-160 complex [cytosol] 32 × [Complex:R-CEL-157712] Nup62 Complex [nuclear envelope] 32 × [Complex:R-CEL-9634183] Nup93 complex [nuclear envelope] 48 × [EntityWithAccessionedSequence:R-CEL-157718] rae-1 [nuclear envelope]
inDisease	false
inferredFrom	[Complex:R-HSA-157689] Nuclear Pore Complex (NPC) [nuclear envelope] - Homo sapiens
isRequired	[Requirement:10919380] Requirement by 'Nuclear Pore Complex (NPC) [nuclear envelope]'
maxDepth	3
name	Nuclear Pore Complex (NPC)
positivelyRegulates	[Requirement:10919380] Requirement by 'Nuclear Pore Complex (NPC) [nuclear envelope]'
producedByEvent	[Reaction:R-CEL-75098] mRNP complex dissociates from cytosolic face of NPC - Caenorhabditis elegans
schemaClass	Complex
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-157689
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Referrals

(physicalEntity)	[CatalystActivity:10962596] SUMO transferase activity of Nuclear Pore Complex (NPC) [nuclear envelope] [CatalystActivity:10964652] structural constituent of nuclear pore activity of Nuclear Pore Complex (NPC) [nuclear envelope] [CatalystActivity:10951769] narrow pore channel activity of Nuclear Pore Complex (NPC) [nuclear envelope]
(input)	[Reaction:R-CEL-2990882] CDK1 phosphorylates NUP98
(output)	[Reaction:R-CEL-75098] mRNP complex dissociates from cytosolic face of NPC
(hasComponent)	[Complex:R-CEL-113815] NPC:NXF1,2:NXT1:EJC:CBC:mRNA [nucleoplasm] [Complex:R-CEL-159259] NPC:NXF1:NXT1:EJC:CBC:mRNA [cytosol]
(regulator)	[Requirement:10919380] Requirement by 'Nuclear Pore Complex (NPC) [nuclear envelope]'
(inferredTo)	[Complex:R-HSA-157689] Nuclear Pore Complex (NPC) [nuclear envelope]

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