Reactome | GMP dissociates from the GBP1 oligomer

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GMP dissociates from the GBP1 oligomer Show undefined attributes

category	dissociation
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10442329
displayName	GMP dissociates from the GBP1 oligomer
eventOf	[Pathway:R-BTA-9953170] GBP-mediated host defense - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9953173] GMP dissociates from the GBP1 oligomer - Homo sapiens
input	[Complex:R-BTA-9947870] GBP1 oligomer:GMP:LPS [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	GMP dissociates from the GBP1 oligomer
output	[SimpleEntity:R-ALL-113578] GMP [cytosol] [DefinedSet:R-BTA-9947912-3] Homologues of S-farn-C589-GBP1 [cytosol] [SimpleEntity:R-ALL-6803081] LPS [peptidoglycan-based cell wall]
precedingEvent	[Reaction:R-BTA-9947887] GBP1 hydrolyzes GDP - Bos taurus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-9953173
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-9953170] GBP-mediated host defense
(inferredTo)	[Reaction:R-HSA-9953173] GMP dissociates from the GBP1 oligomer

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