Reactome | SDS dimers:PXLP convert L-Ser to PYR and NH4+

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SDS dimers:PXLP convert L-Ser to PYR and NH4+ Show undefined attributes

catalystActivity	[CatalystActivity:10440824] L-serine ammonia-lyase activity of PXLP-SDS dimers [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10440826
displayName	SDS dimers:PXLP convert L-Ser to PYR and NH4+
eventOf	[Pathway:R-BTA-977347] Serine metabolism - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9929460] SDS dimers:PXLP convert L-Ser to PYR and NH4+ - Homo sapiens
input	[SimpleEntity:R-ALL-200736] L-Ser [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	SDS dimers:PXLP convert L-Ser to PYR and NH4+ L-serine => NH4(+) + pyruvate
output	[SimpleEntity:R-ALL-31633] NH4+ [cytosol] [SimpleEntity:R-ALL-29398] PYR [cytosol]
precedingEvent	[Reaction:R-BTA-977324] PSPH:Mg2+ dimer dephosphorylates O-P-Ser - Bos taurus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-9929460
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-977347] Serine metabolism
(inferredTo)	[Reaction:R-HSA-9929460] SDS dimers:PXLP convert L-Ser to PYR and NH4+

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