Reactome | LIPT1 transfers lipoyl group from lipoyl-GCSH to DLAT

Schema > Reaction > Entries

LIPT1 transfers lipoyl group from lipoyl-GCSH to DLAT Show undefined attributes

catalystActivity	[CatalystActivity:10411878] N-acyltransferase activity of LIPT1 [mitochondrial matrix]
category	transition
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10439684
displayName	LIPT1 transfers lipoyl group from lipoyl-GCSH to DLAT
eventOf	[Pathway:R-BTA-9857492] Protein lipoylation - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-BTA-6793590] LIPT2 transfers octanoyl group to GCSH - Bos taurus
inferredFrom	[Reaction:R-HSA-9858752] LIPT1 transfers lipoyl group from lipoyl-GCSH to DLAT - Homo sapiens
input	[EntityWithAccessionedSequence:R-BTA-6792585] DLAT [mitochondrial matrix] 2 × [EntityWithAccessionedSequence:R-BTA-6793611] GCSH [mitochondrial matrix]
isInDisease	false
isInferred	true
maxDepth	1
name	LIPT1 transfers lipoyl group from lipoyl-GCSH to DLAT
output	2 × [EntityWithAccessionedSequence:R-BTA-5693951] GCSH [mitochondrial matrix] [EntityWithAccessionedSequence:R-BTA-69969] Lipo-K259-DLAT [mitochondrial matrix]
precedingEvent	[Reaction:R-BTA-6793591] LIAS synthesizes lipoyl-GCSH - Bos taurus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-9858752
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-9857492] Protein lipoylation
(inferredTo)	[Reaction:R-HSA-9858752] LIPT1 transfers lipoyl group from lipoyl-GCSH to DLAT
(precedingEvent)	[Reaction:R-BTA-6793590] LIPT2 transfers octanoyl group to GCSH

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