Reactome | Active FLT3 binds to SOCS2

Schema > Reaction > Entries

category	binding
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10434693
displayName	Active FLT3 binds to SOCS2
eventOf	[Pathway:R-BTA-9706369] Negative regulation of FLT3 - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9706328] Active FLT3 binds to SOCS2 - Homo sapiens
input	[Complex:R-BTA-9604751] Active FLT3 [plasma membrane] [EntityWithAccessionedSequence:R-BTA-1169204] SOCS2 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Active FLT3 binds to SOCS2
output	[Complex:R-BTA-9706226] active FLT3:SOCS2 [plasma membrane]
precedingEvent	[BlackBoxEvent:R-BTA-9604767] FLT3LG dimer:FLT3 dimer autophosphorylates - Bos taurus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-9706328
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-BTA-9706369] Negative regulation of FLT3
(inferredTo)	[Reaction:R-HSA-9706328] Active FLT3 binds to SOCS2

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