Reactome | activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10404695
displayName	activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane]
hasComponent	[Complex:R-BTA-5672720] activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] [CandidateSet:R-ALL-9657567] dual mechanism MAP2K1/2 inhibitors [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-9657583] activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] - Homo sapiens
maxDepth	12
name	activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors
negativelyRegulates	[NegativeRegulation:10404701] Negative regulation by 'activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane]'
producedByEvent	[Reaction:R-BTA-9657599] Dual mechanism MAP2K inhibitors bind MAP2Ks - Bos taurus
schemaClass	Complex
species	[Species:48898] Bos taurus
stId	R-BTA-9657583
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(output)	[Reaction:R-BTA-9657599] Dual mechanism MAP2K inhibitors bind MAP2Ks
(regulator)	[NegativeRegulation:10404701] Negative regulation by 'activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane]'
(inferredTo)	[Complex:R-HSA-9657583] activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane]

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