Reactome | Activated NTRK3 signals through PI3K

Schema > Pathway > Entries

created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10446068
displayName	Activated NTRK3 signals through PI3K
eventOf	[Pathway:R-BTA-9034015] Signaling by NTRK3 (TRKC) - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:262292] positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-BTA-9603419] Activated NTRK3 binds SRC - Bos taurus [Reaction:R-BTA-9603420] Activated NTRK3 promotes SRC autophosphorylation - Bos taurus
inferredFrom	[Pathway:R-HSA-9603381] Activated NTRK3 signals through PI3K - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Activated NTRK3 signals through PI3K
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48898] Bos taurus
stId	R-BTA-9603381
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-BTA-9034015] Signaling by NTRK3 (TRKC)
(inferredTo)	[Pathway:R-HSA-9603381] Activated NTRK3 signals through PI3K

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