Reactome | NTRK3 dimers trans-autophosphorylate

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NTRK3 dimers trans-autophosphorylate Show undefined attributes

catalystActivity	[CatalystActivity:10431691] protein tyrosine kinase activity of NTF3:NTRK3 homodimer [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10431693
displayName	NTRK3 dimers trans-autophosphorylate
eventOf	[Pathway:R-BTA-9034013] NTF3 activates NTRK3 signaling - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-BTA-9603419] Activated NTRK3 binds SRC - Bos taurus
goBiologicalProcess	[GO_BiologicalProcess:172228] positive regulation of neurotrophin TRK receptor signaling pathway
inferredFrom	[Reaction:R-HSA-9034714] NTRK3 dimers trans-autophosphorylate - Homo sapiens
input	10 × [SimpleEntity:R-ALL-113592] ATP [cytosol] [Complex:R-BTA-9034025] NTF3:NTRK3 homodimer [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	NTRK3 dimers trans-autophosphorylate
output	10 × [SimpleEntity:R-ALL-29370] ADP [cytosol] [Complex:R-BTA-9034727] NTF3:p-5Y-NTRK3 homodimer [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-9034714
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(precedingEvent)	[Reaction:R-BTA-9603419] Activated NTRK3 binds SRC
(hasEvent)	[Pathway:R-BTA-9034013] NTF3 activates NTRK3 signaling
(inferredTo)	[Reaction:R-HSA-9034714] NTRK3 dimers trans-autophosphorylate

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