Reactome | Interleukin-33 signaling

Schema > Pathway > Entries

created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10444700
displayName	Interleukin-33 signaling
eventOf	[Pathway:R-BTA-446652] Interleukin-1 family signaling - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:2454443] interleukin-33-mediated signaling pathway
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-BTA-448629] IL33 binds IL1RL1 - Bos taurus [Reaction:R-BTA-448603] IL33:IL1RL1 binds IL1RAP-1 - Bos taurus
inferredFrom	[Pathway:R-HSA-9014843] Interleukin-33 signaling - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Interleukin-33 signaling
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48898] Bos taurus
stId	R-BTA-9014843
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-BTA-446652] Interleukin-1 family signaling
(inferredTo)	[Pathway:R-HSA-9014843] Interleukin-33 signaling

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