Reactome | IL33:IL1RL1 binds IL1RAP-1

Schema > Reaction > Entries

category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10365934
displayName	IL33:IL1RL1 binds IL1RAP-1
eventOf	[Pathway:R-BTA-9014843] Interleukin-33 signaling - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-448603] IL33:IL1RL1 binds IL1RAP-1 - Homo sapiens
input	[EntityWithAccessionedSequence:R-BTA-445745] IL1RAP [plasma membrane] [Complex:R-BTA-448601] IL1RL1:IL33 [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	IL33:IL1RL1 binds IL1RAP-1
output	[Complex:R-BTA-448571] IL33:IL1RL1:IL1RAP-1 [plasma membrane]
precedingEvent	[Reaction:R-BTA-448629] IL33 binds IL1RL1 - Bos taurus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-448603
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-BTA-9014843] Interleukin-33 signaling
(inferredTo)	[Reaction:R-HSA-448603] IL33:IL1RL1 binds IL1RAP-1

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