Reactome | HDL assembly

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HDL assembly Show undefined attributes

created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10444246
displayName	HDL assembly
eventOf	[Pathway:R-BTA-8963898] Plasma lipoprotein assembly - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:358072] high-density lipoprotein particle assembly
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-BTA-264758] BMP1-3:Zn2+ cleaves pro-APOA1 to APOA1 - Bos taurus [Reaction:R-BTA-5682084] ZDHCC8 transfers PALM from PALM-CoA to ABCA1 tetramer - Bos taurus [Reaction:R-BTA-5682103] 4xPALM-C-ABCA1 tetramer translocates from ER membrane to plasma membrane - Bos taurus [Reaction:R-BTA-5682101] PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer - Bos taurus [Reaction:R-BTA-216727] 4xPALM-C-p-2S-ABCA1 tetramer binds APOA1 - Bos taurus [Reaction:R-BTA-216723] 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane - Bos taurus [Reaction:R-BTA-216757] 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane - Bos taurus [Reaction:R-BTA-216756] Apolipoprotein A-I binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle - Bos taurus [Reaction:R-BTA-349657] pre-beta HDL binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle - Bos taurus
inferredFrom	[Pathway:R-HSA-8963896] HDL assembly - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	HDL assembly
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48898] Bos taurus
stId	R-BTA-8963896
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-8963898] Plasma lipoprotein assembly
(inferredTo)	[Pathway:R-HSA-8963896] HDL assembly

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