Reactome | CDK4,CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); CDK4,CDK6:CCND; (CDK4,CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm]

Schema > CandidateSet > Entries

compartment	[Compartment:7660] nucleoplasm
consumedByEvent	[Reaction:R-BTA-8942836] CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6 - Bos taurus
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10426334
displayName	CDK4,CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); CDK4,CDK6:CCND; (CDK4,CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm]
hasCandidate	[Complex:R-BTA-8949875] CDK4,CDK6:CCND:p-Y88-CDKN1B [nucleoplasm] - Bos taurus
hasMember	[Complex:R-BTA-141298] Cyclin D:CDK4,CDK6:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] - Bos taurus [DefinedSet:R-BTA-9758263] CDK4:CCND [nucleoplasm] - Bos taurus [DefinedSet:R-BTA-9758262] CDK6:CCND [nucleoplasm] - Bos taurus
inDisease	false
inferredFrom	[CandidateSet:R-HSA-8949874] CDK4,CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); CDK4,CDK6:CCND; (CDK4,CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] - Homo sapiens
maxDepth	5
name	CDK4,CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); CDK4,CDK6:CCND; (CDK4,CDK6:CCND:p-Y88-CDKN1B)
producedByEvent	[BlackBoxEvent:R-BTA-8942803] Translocation of CDK4/6:CCND complexes from the cytoplasm to the nucleus - Bos taurus
schemaClass	CandidateSet
species	[Species:48898] Bos taurus
stId	R-BTA-8949874

(input)	[Reaction:R-BTA-8942836] CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6
(output)	[BlackBoxEvent:R-BTA-8942803] Translocation of CDK4/6:CCND complexes from the cytoplasm to the nucleus
(inferredTo)	[CandidateSet:R-HSA-8949874] CDK4,CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); CDK4,CDK6:CCND; (CDK4,CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm]

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