Reactome | CDK4,CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C) [cytosol]

Schema > Complex > Entries

compartment	[Compartment:70101] cytosol
consumedByEvent	[Reaction:R-BTA-8942607] Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes - Bos taurus
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10426201
displayName	CDK4,CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C) [cytosol]
hasComponent	[Complex:R-BTA-8941896] CDK4,CDK6:CCND [cytosol] [CandidateSet:R-BTA-8941923] CDKN1A,CDKN1B,(CDKN1C) [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-8941921] CDK4,CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C) [cytosol] - Homo sapiens
maxDepth	4
memberOf	[CandidateSet:R-BTA-8949872] CDK4,CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); CDK4,CDK6:CCND; (CDK4,CDK6:CCND:p-Y88-CDKN1B) [cytosol] - Bos taurus
name	CDK4,CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C)
producedByEvent	[Reaction:R-BTA-8941915] Cip/Kip CDK inhibitors bind CDK4/6:CCND complexes - Bos taurus
schemaClass	Complex
species	[Species:48898] Bos taurus
stId	R-BTA-8941921
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-BTA-8942607] Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes
(output)	[Reaction:R-BTA-8941915] Cip/Kip CDK inhibitors bind CDK4/6:CCND complexes
(hasMember)	[CandidateSet:R-BTA-8949872] CDK4,CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); CDK4,CDK6:CCND; (CDK4,CDK6:CCND:p-Y88-CDKN1B) [cytosol]
(inferredTo)	[Complex:R-HSA-8941921] CDK4,CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C) [cytosol]

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