Reactome | RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known

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RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Show undefined attributes

created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10445896
displayName	RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
eventOf	[Pathway:R-BTA-8878171] Transcriptional regulation by RUNX1 - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-BTA-8878054] HIPK2 phosphorylates RUNX1 - Bos taurus [Reaction:R-BTA-8878056] RUNX1:CBFB binds EP300 - Bos taurus [Reaction:R-BTA-8878050] HIPK2 phosphorylates RUNX1 and EP300 - Bos taurus [Reaction:R-BTA-8937989] RUNX1 binds PRC1 complexes - Bos taurus [Reaction:R-BTA-8938217] RUNX1 binds the SWI/SNF complex - Bos taurus
inferredFrom	[Pathway:R-HSA-8939243] RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48898] Bos taurus
stId	R-BTA-8939243
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-8878171] Transcriptional regulation by RUNX1
(inferredTo)	[Pathway:R-HSA-8939243] RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known

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