Reactome | RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known

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RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Show undefined attributes

authored	[InstanceEdit:8938982] Orlic-Milacic, Marija, 2016-09-14
created	[InstanceEdit:8939244] Orlic-Milacic, Marija, 2016-09-16
dbId	8939243
displayName	RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
edited	[InstanceEdit:9005626] Orlic-Milacic, Marija, 2017-05-09
eventOf	[Pathway:R-HSA-8878171] Transcriptional regulation by RUNX1 - Homo sapiens
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-HSA-8878054] HIPK2 phosphorylates RUNX1 - Homo sapiens [Reaction:R-HSA-8878056] RUNX1:CBFB binds EP300 - Homo sapiens [Reaction:R-HSA-8878050] HIPK2 phosphorylates RUNX1 and EP300 - Homo sapiens [Reaction:R-HSA-8937989] RUNX1 binds PRC1 complexes - Homo sapiens [Reaction:R-HSA-8938217] RUNX1 binds the SWI/SNF complex - Homo sapiens
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:8878049] Roles of HIPK1 and HIPK2 in AML1- and p300-dependent transcription, hematopoiesis and blood vessel formation [LiteratureReference:8878057] PEBP2-beta/CBF-beta-dependent phosphorylation of RUNX1 and p300 by HIPK2: implications for leukemogenesis [LiteratureReference:8937990] Direct recruitment of polycomb repressive complex 1 to chromatin by core binding transcription factors [LiteratureReference:8938224] The human SWI/SNF complex associates with RUNX1 to control transcription of hematopoietic target genes
modified	[InstanceEdit:10740525] Wright, Adam, 2024-03-08
name	RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
orthologousEvent	[Pathway:R-RNO-8939243] RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known - Rattus norvegicus [Pathway:R-CEL-8939243] RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known - Caenorhabditis elegans [Pathway:R-DME-8939243] RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known - Drosophila melanogaster [Pathway:R-GGA-8939243] RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known - Gallus gallus [Pathway:R-SSC-8939243] RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known - Sus scrofa [Pathway:R-BTA-8939243] RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known - Bos taurus [Pathway:R-CFA-8939243] RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known - Canis familiaris [Pathway:R-MMU-8939243] RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known - Mus musculus
releaseDate	2017-06-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9005627] Ito, Yoshiaki, 2016-12-20 [InstanceEdit:9005628] Chuang, Linda Shyue Huey, 2016-12-20
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-8939243
summation	[Summation:8939460] The transcriptional activity of the RUNX1:CBFB complex is re...

Referrals

(hasEvent)

[Pathway:R-HSA-8878171] Transcriptional regulation by RUNX1